Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
Genetic screens are a powerful tool to discover genes that are important in ngetikin immune cell development and function.The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose.We used a Tol2-based gene-breaking transposon to induce mutations in